Oral Microbiota at Day +28 Post-HCT Tied to Chronic Graft-Versus-Host Disease

Posted: September 4, 2025
A study of 37 patients undergoing allogeneic hematopoietic cell transplantation found a significant association between the composition of oral microbiota at day +28 post-transplant and the risk of chronic graft-versus-host disease (cGVHD). Streptococcus sanguinis and Prevotella loescheii in the plaque at day +28 were linked to cGVHD. Metagenomic analysis identified microbial pathways like ethanolamine utilization and glycerol metabolism, attributed to S. sanguinis, as potential contributors to cGVHD development. These findings suggest a possible early intervention target to mitigate long-term immunologic complications post-transplant.

This article summary was generated by AI. To view the full article, click the link here: https://pubmed.ncbi.nlm.nih.gov/40905099/
Views: 1
Sponsors
Townie Perks
Townie® Poll
This is the poll questions
  
The Dentaltown Team, Member Services Specialist
Phone: +1-480-445-9710
Email: support@dentaltown.com
©2026 Dentaltown, a division of Farran Media • All Rights Reserved
9633 S. 48th Street Suite 200 • Phoenix, AZ 85044 • Phone:+1-480-598-0001 • Fax:+1-480-598-3450